Risperidone Orodispersible Tablets were prepared by three different methods. In the first formulatrion, cross povidone was used as superdisintegrant.In the second method cross povidone along with camphor was used in the preparation(Sublimation technology).In the last method evolution of carbon di oxide as disintegration mechanism was used.The prepared Risperidone Orodispersible tablets were evaluated for hardness, friability, weight variation, disintegration, wetting time, drug content and in vitro dissolution studies.The disintegration time of the Orodispersible were found to be be less than 30 seconds. Formulation prepared by using cross povidine (20mg) and Camphor (15mg) was selected as the best formulation (F6). The present study demonstrated potentials for rapid absorption, improved bioavailability, effective therapy and patient compliance.
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